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TOPIC TITLE: slow vs. fast metabolizers
Created On 8/23/15 10:38 PM
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Posts: 104
Joined: Aug 2011

8/23/15 10:38 PM
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Can you explain to me the concept of slow vs. fast metabolizers of medicine? I mean, I tried to read up on it a bit, but I still don't get it.

Let's just say G-d knew I had a sense of humor.

Dr. Price MD

Posts: 1989
Joined: Jan 2006

8/24/15 8:54 AM
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Medications can be metabolized by liver enzymes called the cytochrome P450 system.
Genetic tests are available to test some of the common enzymes involved in metabolizing medications.
If you are an ultra-rapid metabolizer then you may need a higher dose of the medication for it to work
And may not get the typical side effects and lower dosages.
If you are a slow metabolizer then you may respond to a low dose and experience side effects at high dosages.
The faster you clear the medication=fast metabolizer. The slower you clear it=slow metabolizer.

Rabbi Price, M.D.


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